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The Bio-Performance Skin Filler Serum Duo from Shiseido works together to boost skin's suppleness, firmness and resilience. The Infill Serum is designed for your nighttime routine - with the high molecular weight hyaluronic acid bringing deep hydration to your complexion - while the Full Expansion Serum is targeted to your daytime ritual, with the acid applied in the evening being re-expanded to fill fine lines and wrinkles.